Análisis de asociación genómico para crecimiento individual y eficiencia alimentaria colectiva en conejos bajo dos regímenes de alimentación

Authors:

Sánchez J.P., Legarra A., Velasco M., Piles M., Rafel O., González O., Ballester M.

Publication date:

7 May 2019

Full title:

Análisis de asociación genómico para crecimiento individual y eficiencia alimentaria colectiva en conejos bajo dos regímenes de alimentación

Genome wide association study of individual growth and cage feed efficiency in rabbits under two feeding regimens

Publishing information:

XVIII Jornadas sobre producción animal, 7-8 May 2019, Campus de Aula Dei, Zaragoza, Spain

Abstract:

Our objective was to identify rabbit genomic regions associated with growth (ADGv), feed intake (FIv), feed conversion ratio (FCRv) and residual feed intake (RFIv) recorded under full feeding, as well as with growth under restricted feeding (ADGr). To achieve this aim, 114,604 SNPs were evaluated in 438 rabbits. Three different models for testing the associations were used. The one returning the largest number of significant associations combines LD and linkage information, this provided significance at genome-wide level. The other two approaches only returned significant associations at chromosome level. Overall, at this level, ADGv resulted associated with 25 regions, ADGr with two, FIv with one and RFIv with two regions. Among the 29 candidate genes identified within these regions, four could have a pleiotropic effect among ADGv and RFIv. FTO was also previously associated with growth in rabbits, and some genes associated with ADGr could be linked to feeding behavior.

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